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Despite their potential, key challenges for intranasal lipid-based nanoparticles delivery include rapid mucociliary clearance, the selective penetration of the nasal mucosal barrier, and the precise targeting of specific brain regions

Immune cells responsible for inflammation express the vitamin D receptor, and vitamin D successfully suppresses chronic inflammation in multiple settings, while vitamin D deficiency is associated with a pro-inflammatory state (Mohd 2022

It plays a multi-target, integrated regulatory role through modulation of signaling pathways such as NF-B, MAPK, and Nrf2

Involvement of the Cys1093 residue oxidation in TRPM4 channel activation has also a significant role in oxidative stress dependent (without ATP depletion) activation and desensitization of TRPM4

When comparing the Byr2-RBD region of P